If you have multiple pick-up and drop off stops in your shipments, and different items being picked up and dropped off at each stop - you can manage this using the "manage pickup items" and "manage dropoff items" buttons.
1. Create your shipment: Enter all of the items being picked up and dropped off in the "Items Shipped" section.
Then, add your pickup and dropoff stops. Use the "+Add Pickup Stop" and "+Add Dropoff stop" to add additional stops.
2. Click on "Manage Pickup Items" (or "Manage Dropoff Items) to specify which items are being picked up or dropped off at which locations.
In the window that comes up, drag and drop your items from one stop to another, and hit close to save.